Two Hunters in Wyoming Possibly First Americans to Die from Zombie Deer Disease After Eating Prion-Infected Venison
What causes proteins to become prions? Could mRNA vaccines' "unintended" proteins play a role?
Two hunters in Wyoming have potentially become the first Americans to die from chronic wasting disease (CWD) after consuming infected venison. The disease, commonly known as zombie deer disease, had fatal consequences for the hunters, with symptoms including confusion, aggression, seizures, and ultimately death. The study raises concerns about the transmission of CWD from animals to humans and highlights the need for further investigation into the risks associated with consuming contaminated deer meat.
CWD is caused by misfolded proteins known as prions, which spread throughout the central nervous system, leading to brain tissue and organ damage.
The Link Between Protein Folding and Misfolded Proteins
Proteins play crucial roles in the body, carrying out various functions essential for life. Central to their functionality is the process of protein folding, where a protein adopts a specific three-dimensional shape that enables it to perform its designated task effectively. However, this intricate process does not always proceed flawlessly, leading to misfolded proteins. Understanding why protein folding sometimes fails sheds light on the potential implications for human health.
Factors Contributing to Protein Folding Failure
Genetic Mutations: Mutations in the DNA sequence encoding a protein can alter the amino acid sequence, affecting the protein's ability to achieve its native fold correctly. Inherited mutations, such as those linked to cystic fibrosis or sickle cell anemia, exemplify this scenario.
Errors in Protein Synthesis: During protein synthesis, errors can occur as the ribosome reads the genetic instructions, resulting in misincorporation of amino acids. These mistakes can compromise the proper folding of proteins, with estimates suggesting errors in up to 1 in every 7 proteins.
Intrinsic Challenges in Protein Folding: Even in the absence of mutations or synthesis errors, proteins may fail to fold correctly due to inherent complexities in the folding process. Factors like changes in cellular conditions, such as pH and temperature, can further impede proper protein folding.
Consequences of Misfolded Proteins
1. Loss of Function:
Insufficient folding of specific proteins can lead to a functional deficiency, impacting critical cellular processes. Diseases like cystic fibrosis and Tay-Sachs disease illustrate how inadequate protein folding results in the inability of proteins to carry out their intended functions.
2. Aggregation and Cellular Stress:
Misfolded proteins can form aggregates within cells, disrupting normal cellular activities. These aggregates are implicated in various neurodegenerative diseases, including Alzheimer's and Parkinson's disease, where the accumulation of misfolded proteins contributes to cellular dysfunction and degeneration.
3. Prion Disease:
One notable example of misfolded proteins wreaking havoc within the body is the prion protein associated with Creutzfeldt-Jakob disease, also known as mad cow disease. This misfolded protein not only adopts an aberrant structure itself but also induces other functional proteins to misfold, perpetuating a cascade of pathological events.
“Unintended” Proteins from COVID-19 Vaccines
Proteins, the workhorses of biological systems, rely on precise folding mechanisms to function effectively. However, deviations from the norm in protein folding can lead to the generation of misfolded proteins with potentially detrimental consequences. Recent studies have shed light on how messenger RNA (mRNA) vaccines for COVID-19 may inadvertently trigger the production of "unintended" proteins, raising questions about their folding patterns and implications for human health.
Challenges in mRNA Vaccine-Induced Protein Production: mRNA vaccines introduce artificial mRNA sequences into cells to stimulate the production of specific proteins, such as the spike protein of the coronavirus. However, modifications in the mRNA sequence, like pseudouridine used in COVID-19 vaccines, may increase the likelihood of inducing frameshifted proteins that deviate from the intended structure.
Consequences of Vaccine-Induced Mutant Proteins
1. Functional Impairment:
Mutant proteins resulting from mRNA vaccine-induced frameshifts may exhibit altered structures that impact their functionality. While some immune responses to these proteins have been observed, their potential effects on cellular processes and immune reactions warrant further investigation.
2. Cellular Stress and Immune Responses:
The presence of unintended proteins can lead to cellular stress and trigger immune responses in the body. Understanding how these proteins interact with cellular machinery and immune components is crucial for evaluating their impact on overall health.
While some may consider the following a stretch, we should consider whether the unintended proteins created by covid mRNA vaccines could potentially become prions and then transmit to humans and animals…or mimic animal prion diseases. In the least, could immune system stress make humans more susceptible to prion diseases in animals?
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Ive been watching this since MRNA & the risk of Prion disease was published in 2021
https://scivisionpub.com/pdfs/covid19-rna-based-vaccines-and-the-risk-of-prion-disease-1503.pdf
Prion proteins have been found in cadavers, contaminated medical treatments, farmed fish and even human tears.
A few things to note , prion proteins can’t be cleaned, disinfected or sanitized. The environment can be contaminated , and it is known they can be transmissible :
“Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases that affect humans and animals. They are always fatal. TSEs can be transmitted through contact with infected tissue, body fluids, or contaminated medical instruments. Normal sterilization procedures such as boiling or irradiating materials do not prevent transmission of TSEs.”
The early covid tests (the ones that damaged the olfactory epithelium) may have actually increased the risk of transmission of prion diseases among the vaxxed / unvaxxed population…